Nicolas Cage, Eva Mendes, Val Kilmer, Fairuza Balk, Shawn Hatosy, Jennifer Coolidge, Tom Bower, Vondie Curtis-Hall, Irma P. Hall, Shea Whigham, Michael Shannon, Brad Dourif, Xzibit, Denzel Whitaker, Joe Nemmers
Terrence McDonagh is a New Orleans Police sergeant, who recieves a medal and a promotion to lieutenant for heroism during Hurricane Katrina. Due to his heroic act, McDonagh injures his back and becomes addicted to prescription pain medication. He then finds himself involved with a drug dealer who is suspected of murdering a family of African immigrants.