Chris Rock, Laurence Fishburne, David Hyde Pierce, Brandy Norwood, Bill Murray, Molly Shannon, William Shatner, Ron Howard, Sherry Lynn, Mickie McGowan, Chris Elliott, Elena Franklin, Kid Rock, Uncle Kracker, Carlos Alazraqui
A white blood cell policeman, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.