Sam Rockwell, Jon Favreau, Tracy Morgan, Penélope Cruz, Nicolas Cage, Dee Bradley Baker, Bill Nighy, Will Arnett, Zach Galifianakis, Kelli Garner, Steve Buscemi, Jared Lavette, Micah Lavette, Niecy Nash-Betts, Loudon Wainwright III
A team of trained secret agent animals, guinea pigs Darwin, Hurley, Juarez, Blaster, mole Speckles, and fly Mooch takes on a mission for the US government to stop evil Leonard Saber, who plans to destroy the world with household appliances. But the government shuts them down and they are sentenced to a pet shop. Can they escape to defeat the villain and save the world?